BDBM50274635 (3-((6-amino-8-mercapto-2-(2-methoxyethoxy)-9H-purin-9-yl)methyl)phenyl)methyl(methyl)phosphinic acid::CHEMBL519690

SMILES COCCOc1nc(N)c2[nH]c(=S)n(Cc3cccc(CP(C)(O)=O)c3)c2n1

InChI Key InChIKey=UTMHSCRYHINWDI-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50274635   

TargetToll-like receptor 7(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50274635((3-((6-amino-8-mercapto-2-(2-methoxyethoxy)-9H-pur...)
Affinity DataEC50:  10nMAssay Description:Agonist activity at human TLR7 by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetToll-like receptor 7(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50274635((3-((6-amino-8-mercapto-2-(2-methoxyethoxy)-9H-pur...)
Affinity DataEC50:  10nMAssay Description:Agonist activity at TLR7 in human PBMC cells assessed as stimulation of interferon releaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed