BDBM50274602 CHEMBL4128324

SMILES CNC(=O)C(=Cc1ccc(o1)-c1nc2cnc3[nH]ccc3c2n1C1CCCCC1)C#N

InChI Key InChIKey=JHABFZDOCCBNTO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50274602   

TargetTyrosine-protein kinase JAK3(Human)
Eberhard Karls University T£Bingen

Curated by ChEMBL
LigandPNGBDBM50274602(CHEMBL4128324)
Affinity DataIC50: 23nMAssay Description:Inhibition of recombinant human JAK3 (781 to 1124 residues) expressed in baculovirus expression system assessed as reduction in polypeptide substrate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/13/2020
Entry Details Article
PubMed