BDBM50274386 4-({3-Chloro-4-[(1-methyl-1H-imidazol-2-yl)thio]phenyl}-amino)-7-[(1E)-5-(diethylamino)pent-1-enyl]quinoline-3-carbonitrile::CHEMBL483398

SMILES CCN(CC)CCC\C=C\c1ccc2c(Nc3ccc(Sc4nccn4C)c(Cl)c3)c(cnc2c1)C#N

InChI Key InChIKey=GJTMJMUIFFQIQN-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50274386   

TargetDual specificity mitogen-activated protein kinase kinase 1(Human)
Wyeth Research

Curated by ChEMBL

LigandBDBM50274386(4-({3-Chloro-4-[(1-methyl-1H-imidazol-2-yl)thio]ph...)Copy SMILESCopy InChI

Affinity DataIC50: 25nMAssay Description:Inhibition of MEK1 by raf/MEK1/MAPK coupled assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
1/11/2010
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