BDBM50274258 2-(6,8-Dichloro-2-(4-methoxyphenyl)imidazo[1,2-a]pyridin-3-yl)-N,N-dipropylacetamide::CHEMBL509917

SMILES CCCN(CCC)C(=O)Cc1c(nc2c(Cl)cc(Cl)cn12)-c1ccc(OC)cc1

InChI Key InChIKey=UHHAJQVIKPJWKL-UHFFFAOYSA-N

Data  3 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50274258   

TargetTranslocator protein(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50274258(2-(6,8-Dichloro-2-(4-methoxyphenyl)imidazo[1,2-a]p...)
Affinity DataEC50:  571nMAssay Description:Inhibition of TSPO (unknown origin) in mouse MA-10 cells assessed as increase in steroid steroidogenesisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetTranslocator protein(Rat)
Universita Degli Studi Di Bari

Curated by ChEMBL
LigandPNGBDBM50274258(2-(6,8-Dichloro-2-(4-methoxyphenyl)imidazo[1,2-a]p...)
Affinity DataKi:  0.310nMAssay Description:Displacement of [3H]PK11195 from peripheral benzodiazepine receptor in Sprague-Dawley rat cerebral cortex membrane by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed
TargetTranslocator protein(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50274258(2-(6,8-Dichloro-2-(4-methoxyphenyl)imidazo[1,2-a]p...)
Affinity DataKi:  0.537nMAssay Description:Inhibition of TSPO (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetTranslocator protein(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50274258(2-(6,8-Dichloro-2-(4-methoxyphenyl)imidazo[1,2-a]p...)
Affinity DataKi:  0.537nMAssay Description:Inhibition of TSPO (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed