BDBM50274204 4-({3-Chloro-4-[(1-methyl-1H-imidazol-2-yl)thio]phenyl}-amino)-7-[(1E)-4-hydroxybut-1-enyl]-6-methoxyquinoline-3-carbonitrile::CHEMBL520025

SMILES COc1cc2c(Nc3ccc(Sc4nccn4C)c(Cl)c3)c(cnc2cc1\C=C\CCO)C#N

InChI Key InChIKey=JHSZPNHCJKIYES-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50274204   

TargetDual specificity mitogen-activated protein kinase kinase 1(Human)
Wyeth Research

Curated by ChEMBL

LigandBDBM50274204(4-({3-Chloro-4-[(1-methyl-1H-imidazol-2-yl)thio]ph...)Copy SMILESCopy InChI

Affinity DataIC50: 5nMAssay Description:Inhibition of MEK1 by raf/MEK1/MAPK coupled assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
1/11/2010
Entry Details Article
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