BDBM50274173 CHEMBL4130236

SMILES S=C(NCCCCCCCCNC(=S)NC12CC3CC(CC(C3)C1)C2)NC12CC3CC(CC(C3)C1)C2

InChI Key

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50274173   

TargetBifunctional epoxide hydrolase 2(Human)
University of California Davis

Curated by ChEMBL
LigandPNGBDBM50274173(CHEMBL4130236)
Affinity DataIC50: 9.80nMAssay Description:Inhibition of recombinant human sEH expressed in baculovirus expression system using CMNPC as substrate preincubated for 5 mins followed by substrate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/12/2020
Entry Details Article
PubMed
TargetBifunctional epoxide hydrolase 2(Rat)
University of California Davis

Curated by ChEMBL
LigandPNGBDBM50274173(CHEMBL4130236)
Affinity DataIC50: 374nMAssay Description:Inhibition of rat sEH using CMNPC as substrate preincubated for 5 mins followed by substrate addition measured for 10 mins by fluorescent based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/12/2020
Entry Details Article
PubMed
TargetBifunctional epoxide hydrolase 2(Mouse)
University of California Davis

Curated by ChEMBL
LigandPNGBDBM50274173(CHEMBL4130236)
Affinity DataIC50: 1.17E+3nMAssay Description:Inhibition of recombinant mouse sEH expressed in baculovirus expression system using CMNPC as substrate preincubated for 5 mins followed by substrate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/12/2020
Entry Details Article
PubMed