BDBM50274163 CHEMBL4128495

SMILES Clc1cc(\C=C\c2ccc(cc2)N2CCN(CC2)S(=O)(=O)CC#N)cc(c1)-c1ccncc1

InChI Key InChIKey=PULDBKKJCZWEDM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50274163   

TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
Temple University

Curated by ChEMBL
LigandPNGBDBM50274163(CHEMBL4128495)
Affinity DataIC50: 6nMAssay Description:Inhibition of recombinant CYP17 (unknown origin) expressed in human AD293 cells using [21-3H]17alpha-hydroxypregnenolone as substrate preincubated fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details Article
PubMed