BDBM50274075 CHEMBL1561896

SMILES COc1cccc(COC(=O)c2nn(nc2N)-c2ccccc2)c1

InChI Key InChIKey=PVXSYGKEPLNOTR-UHFFFAOYSA-N

Data  4 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50274075   

TargetAmine oxidase [flavin-containing] B(Human)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50274075(CHEMBL1561896)
Affinity DataIC50: 100nMAssay Description:Inhibition of recombinant human MAO-B expressed in baculovirus infected BTI insect cells using tyramine as substrate preincubated for 30 mins followe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2020
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50274075(CHEMBL1561896)
Affinity DataIC50: 4.70E+3nMAssay Description:Inhibition of recombinant human MAO-A expressed in baculovirus infected BTI insect cells using tyramine as substrate preincubated for 30 mins followe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2020
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50274075(CHEMBL1561896)
Affinity DataKi:  19nMAssay Description:Displacement of [3H]ZM241385 from A2A receptor in human HeLa cell membranes after 30 mins by beta-scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2020
Entry Details Article
PubMed
TargetAdenosine receptor A2b(Human)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50274075(CHEMBL1561896)
Affinity DataKi:  190nMAssay Description:Displacement of [3H]DPCPX from human A2B receptor expressed in cell membranes after 30 mins by beta-scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2020
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50274075(CHEMBL1561896)
Affinity DataKi:  220nMAssay Description:Displacement of [3H]DPCPX from human A1 receptor expressed in cell membranes after 60 mins by beta-scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2020
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50274075(CHEMBL1561896)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]NECA from A3 receptor in human HeLa cell membranes after 180 mins by beta-scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2020
Entry Details Article
PubMed