BDBM50273999 CHEMBL4129702

SMILES CC(C)C[C@H](NC(=O)[C@@H](N)Cc1ccccc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1ccc(CN)cc1)CS(F)(=O)=O

InChI Key InChIKey=GXJAJONKGKXPAI-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50273999   

TargetProteasome subunit beta type-2(Human)
University of Glasgow

Curated by ChEMBL
LigandPNGBDBM50273999(CHEMBL4129702)
Affinity DataIC50: 140nMAssay Description:Inhibition of human 20S constitutive proteasome beta-2 using Bz-VGR-AMC as substrate after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2020
Entry Details Article
PubMed
TargetProteasome subunit beta type-10(Human)
University of Glasgow

Curated by ChEMBL
LigandPNGBDBM50273999(CHEMBL4129702)
Affinity DataIC50: 360nMAssay Description:Inhibition of human 20S immunoproteasome beta-2 using Bz-VGR-AMC as substrate after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2020
Entry Details Article
PubMed
TargetProteasome subunit beta type-5(Human)
University of Glasgow

Curated by ChEMBL
LigandPNGBDBM50273999(CHEMBL4129702)
Affinity DataIC50: 1.25E+5nMAssay Description:Inhibition of human 20S constitutive proteasome beta-5 using Suc-LLVY-AMC as substrate after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2020
Entry Details Article
PubMed
TargetProteasome subunit beta type-8(Human)
University of Glasgow

Curated by ChEMBL
LigandPNGBDBM50273999(CHEMBL4129702)
Affinity DataIC50: 1.37E+5nMAssay Description:Inhibition of human 20S immunoproteasome beta-5 using Suc-LLVY-AMC as substrate after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2020
Entry Details Article
PubMed