BDBM50273949 CHEMBL4128924

SMILES Oc1c(nc2n(CCCC22CCCC2)c1=O)C(=O)NCc1ccc(F)cc1S(=O)(=O)N1CCOCC1

InChI Key InChIKey=WSCAFQQOJGOICA-UHFFFAOYSA-N

Data  1 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50273949   

TargetIntegrase(Human immunodeficiency virus type 1)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50273949(CHEMBL4128924)
Affinity DataEC50:  3nMAssay Description:Inhibition of HIV-1 integrase strand transfer activity assessed as reduction in viral replication in presence of 10% fetal bovine serumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/9/2020
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50273949(CHEMBL4128924)
Affinity DataEC50:  14nMAssay Description:Inhibition of HIV-1 integrase strand transfer activity assessed as reduction in viral replication in presence of 10% fetal bovine serum and 10% human...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/9/2020
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50273949(CHEMBL4128924)
Affinity DataIC50: 11nMAssay Description:Inhibition of HIV1 integrase strand transfer activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/9/2020
Entry Details Article
PubMed