BDBM50273933 (4R*,6aS*,11bR*)-2,3,4,5,6,6a-Hexahydro-3-phenethyl-1H-4,11b-methanobenzofuro[3,2-d]azocine-10-ol::CHEMBL515681

SMILES Oc1ccc2O[C@@H]3CC[C@H]4C[C@@]3(CCN4CCc3ccccc3)c2c1

InChI Key InChIKey=NEVNFUOTQDJGBE-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50273933   

TargetKappa-type opioid receptor(Human)
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50273933((4R*,6aS*,11bR*)-2,3,4,5,6,6a-Hexahydro-3-phenethy...)
Affinity DataKi:  78nMAssay Description:Displacement of [125I]IOXY from human recombinant kappa opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50273933((4R*,6aS*,11bR*)-2,3,4,5,6,6a-Hexahydro-3-phenethy...)
Affinity DataKi:  102nMAssay Description:Displacement of [125I]IOXY from human kappa opioid receptor expressed in CHO cells coexpressing human recombinant KOP after 2 hrs by liquid scintilla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
National Institute On Drug Abuse and The National Institute On Alcohol Abuse and Alcoholism

Curated by ChEMBL
LigandPNGBDBM50273933((4R*,6aS*,11bR*)-2,3,4,5,6,6a-Hexahydro-3-phenethy...)
Affinity DataKi:  352nMAssay Description:Displacement of [125I]IOXY from human mu opioid receptor expressed in CHO cells coexpressing human recombinant MOR after 2 hrs by liquid scintillatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
National Institute On Drug Abuse and The National Institute On Alcohol Abuse and Alcoholism

Curated by ChEMBL
LigandPNGBDBM50273933((4R*,6aS*,11bR*)-2,3,4,5,6,6a-Hexahydro-3-phenethy...)
Affinity DataKi:  740nMAssay Description:Displacement of [125I]IOXY from human recombinant mu opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50273933((4R*,6aS*,11bR*)-2,3,4,5,6,6a-Hexahydro-3-phenethy...)
Affinity DataKi:  4.76E+3nMAssay Description:Displacement of [125I]IOXY from human recombinant delta opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50273933((4R*,6aS*,11bR*)-2,3,4,5,6,6a-Hexahydro-3-phenethy...)
Affinity DataKi: >5.00E+3nMAssay Description:Displacement of [125I]IOXY from human delta opioid receptor expressed in CHO cells coexpressing human recombinant DOR after 2 hrs by liquid scintilla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed