BDBM50273865 CHEMBL461033::tert-Butyl-4-[1-(2-methoxylphenyl)-1H-1,2,3-triazol-4-yl]-3,6-dihydropyridine-1(2H)-carboxylate

SMILES COc1ccccc1-n1cc(nn1)C1=CCN(CC1)C(=O)OC(C)(C)C

InChI Key InChIKey=YFCBVJGIYXXZBZ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50273865   

TargetMetabotropic glutamate receptor 1(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50273865(tert-Butyl-4-[1-(2-methoxylphenyl)-1H-1,2,3-triazo...)
Affinity DataIC50: 590nMAssay Description:Antagonist activity at human mGluR1 expressed in CHO cells assessed as calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Mouse)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50273865(tert-Butyl-4-[1-(2-methoxylphenyl)-1H-1,2,3-triazo...)
Affinity DataIC50: 1.60E+3nMAssay Description:Antagonist activity at mouse mGluR1 expressed in CHO cells assessed as calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50273865(tert-Butyl-4-[1-(2-methoxylphenyl)-1H-1,2,3-triazo...)
Affinity DataIC50: 4.00E+3nMAssay Description:Antagonist activity at human mGluR5 expressed in CHO cells assessed as calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed