BDBM50273859 2-[(S)-1-(4-Fluorophenyl)ethylamino]-5-(1-hydroxycyclopentyl)-5-methylthiazol-4(5H)-one::CHEMBL517874

SMILES C[C@H](NC1=NC(=O)C(C)(S1)C1(O)CCCC1)c1ccc(F)cc1

InChI Key InChIKey=WWOQHILNLFODCY-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50273859   

LigandPNGBDBM50273859(2-[(S)-1-(4-Fluorophenyl)ethylamino]-5-(1-hydroxyc...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human 11beta-HSD2 expressed in CHO cells using [3H]cortisol by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50273859(2-[(S)-1-(4-Fluorophenyl)ethylamino]-5-(1-hydroxyc...)
Affinity DataIC50: 11nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO cells assessed as conversion of cortisone to cortisol by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50273859(2-[(S)-1-(4-Fluorophenyl)ethylamino]-5-(1-hydroxyc...)
Affinity DataKi:  25nMAssay Description:Inhibition of human recombinant 11beta-HSD1 expressed in Escherichia coli using [3H]cortisone by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed