BDBM50273857 2-((S)-1-(4-fluorophenyl)ethylamino)-5-(2-hydroxypropan-2-yl)-5-methylthiazol-4(5H)-one::CHEMBL461879

SMILES C[C@H](NC1=NC(=O)C(C)(S1)C(C)(C)O)c1ccc(F)cc1

InChI Key InChIKey=HYVZYASDRIAOPU-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50273857   

LigandPNGBDBM50273857(2-((S)-1-(4-fluorophenyl)ethylamino)-5-(2-hydroxyp...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human 11beta-HSD2 expressed in CHO cells using [3H]cortisol by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50273857(2-((S)-1-(4-fluorophenyl)ethylamino)-5-(2-hydroxyp...)
Affinity DataIC50: 51nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO cells assessed as conversion of cortisone to cortisol by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50273857(2-((S)-1-(4-fluorophenyl)ethylamino)-5-(2-hydroxyp...)
Affinity DataKi:  65nMAssay Description:Inhibition of human recombinant 11beta-HSD1 expressed in Escherichia coli using [3H]cortisone by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed