BDBM50273824 3-(4-{2-[(S)-1-(4-Fluorophenyl)ethylamino]-5-methyl-4-oxo-4,5-dihydrothiazol-5-yl}phenyl)propanamide::CHEMBL517864

SMILES C[C@H](NC1=NC(=O)C(C)(S1)c1ccc(CCC(N)=O)cc1)c1ccc(F)cc1

InChI Key InChIKey=KCQNICPFVADGBN-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50273824   

LigandPNGBDBM50273824(3-(4-{2-[(S)-1-(4-Fluorophenyl)ethylamino]-5-methy...)
Affinity DataIC50: 680nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO cells assessed as conversion of cortisone to cortisol by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50273824(3-(4-{2-[(S)-1-(4-Fluorophenyl)ethylamino]-5-methy...)
Affinity DataKi:  60nMAssay Description:Inhibition of human recombinant 11beta-HSD1 expressed in Escherichia coli using [3H]cortisone by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed