BDBM50273775 CHEMBL4127363

SMILES Cn1ncc2cc(ccc12)-c1ccc(cn1)C1=NC2(CC2)C(=O)N1C[C@@H]1CCN(C1)C(=O)C1CC1

InChI Key InChIKey=RJSPRRHTVDLJNI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50273775   

TargetFatty acid synthase(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50273775(CHEMBL4127363)
Affinity DataIC50: 460nMAssay Description:Inhibition of human full length FASN using [3H]-acetyl-CoA/malonyl-CoA as substrate after 60 mins in presence of NADPH by scintillation proximity ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/9/2020
Entry Details Article
PubMed