BDBM50273405 2-[(S)-1-(3-Fluorophenyl)ethylamino]-5-(2-hydroxypropan-2-yl)-5-methylthiazol-4(5H)-one::CHEMBL455893

SMILES C[C@H](NC1=NC(=O)C(C)(S1)C(C)(C)O)c1cccc(F)c1

InChI Key InChIKey=KMTVLBMNXSTQSL-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50273405   

LigandPNGBDBM50273405(2-[(S)-1-(3-Fluorophenyl)ethylamino]-5-(2-hydroxyp...)
Affinity DataIC50: 180nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO cells assessed as conversion of cortisone to cortisol by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50273405(2-[(S)-1-(3-Fluorophenyl)ethylamino]-5-(2-hydroxyp...)
Affinity DataKi:  220nMAssay Description:Inhibition of human recombinant 11beta-HSD1 expressed in Escherichia coli using [3H]cortisone by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed