BDBM50273333 1-[4-Methoxy-3-(tetrahydropyran-4-yloxy)phenyl]butan-1-one::CHEMBL456368

SMILES CCCC(=O)c1ccc(OC)c(OC2CCOCC2)c1

InChI Key InChIKey=QCQXJZORBODQNG-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50273333   

TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Georgia State University

Curated by ChEMBL
LigandPNGBDBM50273333(1-[4-Methoxy-3-(tetrahydropyran-4-yloxy)phenyl]but...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human cloned PDE5A1 expressed in Escherichia coli BL21 by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Georgia State University

Curated by ChEMBL
LigandPNGBDBM50273333(1-[4-Methoxy-3-(tetrahydropyran-4-yloxy)phenyl]but...)
Affinity DataIC50: 3.47E+3nMAssay Description:Inhibition of full length human PDE4D2 expressed in Escherichia coli BL21 by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A(Human)
Georgia State University

Curated by ChEMBL
LigandPNGBDBM50273333(1-[4-Methoxy-3-(tetrahydropyran-4-yloxy)phenyl]but...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human cloned PDE7A1 catalytic domain expressed in Escherichia coli BL21 by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Human)
Georgia State University

Curated by ChEMBL
LigandPNGBDBM50273333(1-[4-Methoxy-3-(tetrahydropyran-4-yloxy)phenyl]but...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human cloned PDE9A2 expressed in Escherichia coli BL21 by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Human)
Georgia State University

Curated by ChEMBL
LigandPNGBDBM50273333(1-[4-Methoxy-3-(tetrahydropyran-4-yloxy)phenyl]but...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human cloned PDE2A3 expressed in Escherichia coli BL21 by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Georgia State University

Curated by ChEMBL
LigandPNGBDBM50273333(1-[4-Methoxy-3-(tetrahydropyran-4-yloxy)phenyl]but...)
Affinity DataIC50: 3.47E+3nMAssay Description:Inhibition of full length human PDE4D2 expressed in Escherichia coli BL21 by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed