BDBM50273286 2-Cyano-4-[(spiro[2.5]oct-6-ylmethyl)-amino]-pyrimidine-5-carboxylic acid (1-methyl-4-phenyl-piperidin-4-ylmethyl)-amide::CHEMBL508319

SMILES CN1CCC(CNC(=O)c2cnc(nc2NCC2CCC3(CC3)CC2)C#N)(CC1)c1ccccc1

InChI Key InChIKey=FJKPOCSUBVDARQ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50273286   

TargetProcathepsin L(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50273286(2-Cyano-4-[(spiro[2.5]oct-6-ylmethyl)-amino]-pyrim...)
Affinity DataIC50: 700nMAssay Description:Inhibition of human recombinant cathepsin L by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCathepsin S(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50273286(2-Cyano-4-[(spiro[2.5]oct-6-ylmethyl)-amino]-pyrim...)
Affinity DataIC50: 6nMAssay Description:Inhibition of human recombinant cathepsin S by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCathepsin K(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50273286(2-Cyano-4-[(spiro[2.5]oct-6-ylmethyl)-amino]-pyrim...)
Affinity DataIC50: 170nMAssay Description:Inhibition of human recombinant cathepsin K by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed