BDBM50273218 2-Cyano-4-[(spiro[2.5]oct-6-ylmethyl)-amino]-pyrimidine-5-carboxylic acid phenethyl-amide::CHEMBL515663

SMILES O=C(NCCc1ccccc1)c1cnc(nc1NCC1CCC2(CC2)CC1)C#N

InChI Key InChIKey=DONJICVWTATVDX-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50273218   

TargetProcathepsin L(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50273218(2-Cyano-4-[(spiro[2.5]oct-6-ylmethyl)-amino]-pyrim...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of human recombinant cathepsin L by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCathepsin K(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50273218(2-Cyano-4-[(spiro[2.5]oct-6-ylmethyl)-amino]-pyrim...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of human recombinant cathepsin K by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCathepsin S(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50273218(2-Cyano-4-[(spiro[2.5]oct-6-ylmethyl)-amino]-pyrim...)
Affinity DataIC50: 15nMAssay Description:Inhibition of human recombinant cathepsin S by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed