BDBM50273217 2-cyano-4-((4,4-dimethylcyclohexyl)methylamino)-N-phenethylpyrimidine-5-carboxamide::CHEMBL456756

SMILES CC1(C)CCC(CNc2nc(ncc2C(=O)NCCc2ccccc2)C#N)CC1

InChI Key InChIKey=ZLAPVQNLMNZLGF-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50273217   

TargetProcathepsin L(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50273217(2-cyano-4-((4,4-dimethylcyclohexyl)methylamino)-N-...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of human recombinant cathepsin L by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCathepsin K(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50273217(2-cyano-4-((4,4-dimethylcyclohexyl)methylamino)-N-...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of human recombinant cathepsin K by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCathepsin S(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50273217(2-cyano-4-((4,4-dimethylcyclohexyl)methylamino)-N-...)
Affinity DataIC50: 93nMAssay Description:Inhibition of human recombinant cathepsin S by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed