BDBM50273178 2-cyano-4-(cyclohexylmethoxy)-N-phenethylpyrimidine-5-carboxamide::CHEMBL463180

SMILES O=C(NCCc1ccccc1)c1cnc(nc1OCC1CCCCC1)C#N

InChI Key InChIKey=RQFQNQBNKTWWPR-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50273178   

TargetProcathepsin L(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50273178(2-cyano-4-(cyclohexylmethoxy)-N-phenethylpyrimidin...)
Affinity DataIC50: 780nMAssay Description:Inhibition of human recombinant cathepsin L by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCathepsin K(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50273178(2-cyano-4-(cyclohexylmethoxy)-N-phenethylpyrimidin...)
Affinity DataIC50: 9nMAssay Description:Inhibition of human recombinant cathepsin K by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCathepsin S(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50273178(2-cyano-4-(cyclohexylmethoxy)-N-phenethylpyrimidin...)
Affinity DataIC50: 14nMAssay Description:Inhibition of human recombinant cathepsin S by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed