BDBM50273143 (3,4-Dihydro-1H-pyrido[3,4-b]indol-2(9H)-yl)(2-(pyridin-4-yl)phenyl)methanone::CHEMBL457180

SMILES O=C(N1CCc2c(C1)[nH]c1ccccc21)c1ccccc1-c1ccncc1

InChI Key InChIKey=GBQMFPZNYVGLMF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50273143   

TargetCyclin-dependent kinase 4(Human)
University of Leicester

Curated by ChEMBL
LigandPNGBDBM50273143((3,4-Dihydro-1H-pyrido[3,4-b]indol-2(9H)-yl)(2-(py...)
Affinity DataIC50: 3.90E+4nMAssay Description:Inhibition of human CDK4/GST-cyclin D1 expressed in Sf9 cells assessed as retinoblastoma GST-RB152 phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2(Human)
University of Leicester

Curated by ChEMBL
LigandPNGBDBM50273143((3,4-Dihydro-1H-pyrido[3,4-b]indol-2(9H)-yl)(2-(py...)
Affinity DataIC50: 3.54E+5nMAssay Description:Inhibition of human CDK2/GST-cyclin A expressed in Sf9 cells assessed as histone phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed