BDBM50273076 (3,4-Dihydro-1H-pyrido[3,4-b]indol-2(9H)-yl)(2'-fluorobiphenyl-4-yl)methanone::CHEMBL456584

SMILES Fc1ccccc1-c1ccc(cc1)C(=O)N1CCc2c(C1)[nH]c1ccccc21

InChI Key InChIKey=RYDRDYBUQREBLW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50273076   

TargetCyclin-dependent kinase 4(Human)
University of Leicester

Curated by ChEMBL
LigandPNGBDBM50273076((3,4-Dihydro-1H-pyrido[3,4-b]indol-2(9H)-yl)(2'-fl...)
Affinity DataIC50: 1.70E+4nMAssay Description:Inhibition of human CDK4/GST-cyclin D1 expressed in Sf9 cells assessed as retinoblastoma GST-RB152 phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2(Human)
University of Leicester

Curated by ChEMBL
LigandPNGBDBM50273076((3,4-Dihydro-1H-pyrido[3,4-b]indol-2(9H)-yl)(2'-fl...)
Affinity DataIC50: 3.10E+5nMAssay Description:Inhibition of human CDK2/GST-cyclin A expressed in Sf9 cells assessed as histone phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed