BDBM50272965 CHEMBL4127327

SMILES NC(=O)c1ccc(Oc2cccc(c2)C(=O)N2CCC(CC2)c2ccccc2)cc1

InChI Key InChIKey=UBISEXDTBVRYHF-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50272965   

TargetProtein mono-ADP-ribosyltransferase PARP14(Human)
Mcdaniel College

Curated by ChEMBL
LigandPNGBDBM50272965(CHEMBL4127327)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of full length recombinant His6-tagged human PARP14 WWA/catalytic domain expressed in Escherichia coli BL21(DE3) preincubated for 15 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2020
Entry Details Article
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP14(Human)
Mcdaniel College

Curated by ChEMBL
LigandPNGBDBM50272965(CHEMBL4127327)
Affinity DataIC50: 2.43E+3nMAssay Description:Inhibition of full length recombinant His6-tagged human PARP14 WWA/catalytic domain expressed in Escherichia coli BL21(DE3) preincubated for 15 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2020
Entry Details Article
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP10(Human)
Mcdaniel College

Curated by ChEMBL
LigandPNGBDBM50272965(CHEMBL4127327)
Affinity DataIC50: 575nMAssay Description:Inhibition of full length recombinant His6-tagged human PARP10 expressed in Escherichia coli BL21(DE3) preincubated for 15 mins followed by biotinyla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2020
Entry Details Article
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP10(Human)
Mcdaniel College

Curated by ChEMBL
LigandPNGBDBM50272965(CHEMBL4127327)
Affinity DataIC50: 580nMAssay Description:Inhibition of full length recombinant His6-tagged human PARP10 expressed in Escherichia coli BL21(DE3) preincubated for 15 mins followed by biotinyla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2020
Entry Details Article
PubMed