BDBM50272885 CHEMBL4128304

SMILES Cc1cc(F)ccc1-c1cccn2nc(NC3CCc4[nH]ncc4C3)nc12

InChI Key InChIKey=QYHDMAJURANCPL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50272885   

TargetPresenilin-1(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50272885(CHEMBL4128304)
Affinity DataIC50: 4.57E+3nMAssay Description:Modulation of gamma secretase in human H4 cells expressing human wild type APP assessed as inhibition of amyloid beta 42 production after 22 hrs by e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2020
Entry Details Article
PubMed