BDBM50272873 CHEMBL497454::N-(2-(1H-Indol-3-yl)ethyl)-4'-fluorobiphenyl-2-carboxamide

SMILES Fc1ccc(cc1)-c1ccccc1C(=O)NCCc1c[nH]c2ccccc12

InChI Key InChIKey=GDUJQFIDWWKPIY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50272873   

TargetCyclin-dependent kinase 4(Human)
University of Leicester

Curated by ChEMBL
LigandPNGBDBM50272873(N-(2-(1H-Indol-3-yl)ethyl)-4'-fluorobiphenyl-2-car...)
Affinity DataIC50: 3.80E+4nMAssay Description:Inhibition of human CDK4/GST-cyclin D1 expressed in Sf9 cells assessed as retinoblastoma GST-RB152 phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2(Human)
University of Leicester

Curated by ChEMBL
LigandPNGBDBM50272873(N-(2-(1H-Indol-3-yl)ethyl)-4'-fluorobiphenyl-2-car...)
Affinity DataIC50: 1.22E+6nMAssay Description:Inhibition of human CDK2/GST-cyclin A expressed in Sf9 cells assessed as histone phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed