BDBM50272826 CHEMBL4129090

SMILES CCCCn1ncc2CC(CCc12)Nc1nc2c(cccn2n1)-c1ccc(F)cc1C

InChI Key InChIKey=WPJUJEHPNPQSHY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50272826   

TargetPresenilin-1(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50272826(CHEMBL4129090)
Affinity DataIC50: 2.77E+3nMAssay Description:Modulation of gamma secretase in human H4 cells expressing human wild type APP assessed as inhibition of amyloid beta 42 production after 22 hrs by e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2020
Entry Details Article
PubMed