BDBM50272823 CHEMBL4126617

SMILES CCOC1Cc2c(CC1Nc1nc3c(cccn3n1)-c1cc(F)c(F)c(F)c1C)cnn2CC

InChI Key InChIKey=AYNXXZFORSDCMJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50272823   

TargetPresenilin-1(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50272823(CHEMBL4126617)
Affinity DataIC50: 2.17E+4nMAssay Description:Modulation of gamma secretase in human H4 cells expressing human wild type APP assessed as inhibition of amyloid beta 42 production after 22 hrs by e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2020
Entry Details Article
PubMed