BDBM50272681 CHEMBL4126912

SMILES Nc1c2CCCCc2nc2cccc(N3CCN(CCc4c[nH]c5ccc(cc45)C#N)CC3)c12

InChI Key InChIKey=KLYMURSGAZXARA-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50272681   

Target5-hydroxytryptamine receptor 1A(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50272681(CHEMBL4126912)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human 5-HT1A receptor expressed in HEK293 cells after 60 mins by Eu-cAMP solution based ultra LANCE assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2020
Entry Details Article
PubMed
TargetAcetylcholinesterase(Rat)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50272681(CHEMBL4126912)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of rat cortex AChE using acetylthiocholine iodide as substrate after 20 mins by by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2020
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Rat)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50272681(CHEMBL4126912)
Affinity DataIC50: 1.13E+3nMAssay Description:Inhibition of rat serum BChE using butyrylthiocholine iodide as substrate after 20 mins by by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2020
Entry Details Article
PubMed