BDBM50272625 2-Cyano-4-[2-(1-methyl-piperidin-4-yl)-ethoxy]-6-[(spiro[2.5]oct-6-ylmethyl)-amino]-pyrimidine-5-carboxylic acid benzylamide::CHEMBL498511

SMILES CN1CCC(CCOc2nc(nc(NCC3CCC4(CC4)CC3)c2C(=O)NCc2ccccc2)C#N)CC1

InChI Key InChIKey=UNMHWESVNUCPCW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50272625   

TargetProcathepsin L(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50272625(2-Cyano-4-[2-(1-methyl-piperidin-4-yl)-ethoxy]-6-[...)
Affinity DataIC50: 270nMAssay Description:Inhibition of human recombinant cathepsin L by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed