BDBM50272608 CHEMBL4125688

SMILES C[C@@H](N[C@@H]1CCN(C1)c1cccc(c1)C(F)(F)F)c1cccc2ccccc12

InChI Key InChIKey=CANQNTHVLCZCLU-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50272608   

TargetExtracellular calcium-sensing receptor(Rat)
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM50272608(CHEMBL4125688)
Affinity DataIC50: 9.70nMAssay Description:Agonist activity at CaSR in rat parathyroid cells assessed as inhibition of PTH (1 to 84 residues) production in presence of Cacl2 by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2020
Entry Details Article
PubMed
TargetExtracellular calcium-sensing receptor(Human)
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM50272608(CHEMBL4125688)
Affinity DataEC50:  430nMAssay Description:Agonist activity at human CaSR expressed in CHO cells assessed as increase in intracellular calcium mobilization after 1 hr by Fura-2 dye-based fluor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2020
Entry Details Article
PubMed