BDBM50272591 CHEMBL4128835

SMILES C[C@@H](N[C@H]1CCN(C1)c1ccc(CC(O)=O)cc1)c1cccc2ccccc12

InChI Key InChIKey=RZNUIYPHQFXBAN-UHFFFAOYSA-N

Data  10 IC50  1 EC50

PDB links: 2 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50272591   

TargetCytochrome P450 2C8(Human)
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM50272591(CHEMBL4128835)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of CYP2C8 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2020
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM50272591(CHEMBL4128835)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2020
Entry Details Article
PubMed
TargetExtracellular calcium-sensing receptor(Human)
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM50272591(CHEMBL4128835)
Affinity DataEC50:  93nMAssay Description:Agonist activity at human CaSR expressed in CHO cells assessed as increase in intracellular calcium mobilization after 1 hr by Fura-2 dye-based fluor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCytochrome P450 1A2(Human)
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM50272591(CHEMBL4128835)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of CYP1A2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2020
Entry Details Article
PubMed
TargetCytochrome P450 2A6(Human)
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM50272591(CHEMBL4128835)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of CYP2A6 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2020
Entry Details Article
PubMed
TargetCytochrome P450 2B6(Human)
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM50272591(CHEMBL4128835)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of CYP2B6 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2020
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM50272591(CHEMBL4128835)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2020
Entry Details Article
PubMed
TargetExtracellular calcium-sensing receptor(Rat)
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM50272591(CHEMBL4128835)
Affinity DataIC50: 31nMAssay Description:Agonist activity at CaSR in rat parathyroid cells assessed as inhibition of PTH (1 to 84 residues) production in presence of Cacl2 by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCytochrome P450 2C19(Human)
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM50272591(CHEMBL4128835)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of CYP2C19 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2020
Entry Details Article
PubMed
TargetCytochrome P450 2E1(Human)
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM50272591(CHEMBL4128835)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of CYP2E1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2020
Entry Details Article
PubMed
TargetCytochrome P450 3A4/3A5(Human)
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM50272591(CHEMBL4128835)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of CYP3A4/5 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2020
Entry Details Article
PubMed