BDBM50272515 CHEMBL4128578

SMILES COc1cc(ccc1-c1cnc(OCC(C)C)c(Cl)c1)-c1nnc([nH]1)S(=O)(=O)C1CCC1

InChI Key InChIKey=IPLBYUOAYWBSGB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50272515   

LigandPNGBDBM50272515(CHEMBL4128578)
Affinity DataIC50: 520nMAssay Description:Inhibition of human Nav1.7 expressed in HEK cells clamped to holding potential yielding 20 to 50% inactivation assessed as reduction in peak sodium c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2020
Entry Details Article
PubMed
LigandPNGBDBM50272515(CHEMBL4128578)
Affinity DataIC50: 5.30E+3nMAssay Description:Inhibition of human Nav1.5 expressed in HEK cells at holding potential of -50 mV followed by voltage step to -120 mV by PatchXpress electrophysiology...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2020
Entry Details Article
PubMed