BDBM50272495 CHEMBL4128718

SMILES CC(C)COc1ncc(cc1Cl)-c1ccc(cc1F)-c1nnc([nH]1)S(=O)(=O)C1CCC1

InChI Key InChIKey=GMTNOKLYWUIFIK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50272495   

LigandPNGBDBM50272495(CHEMBL4128718)
Affinity DataIC50: 800nMAssay Description:Inhibition of human Nav1.7 expressed in HEK cells clamped to holding potential yielding 20 to 50% inactivation assessed as reduction in peak sodium c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2020
Entry Details Article
PubMed
LigandPNGBDBM50272495(CHEMBL4128718)
Affinity DataIC50: 2.90E+4nMAssay Description:Inhibition of human Nav1.5 expressed in HEK cells at holding potential of -50 mV followed by voltage step to -120 mV by PatchXpress electrophysiology...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2020
Entry Details Article
PubMed