BDBM50272081 2-[2-Amino-3-(4-hydroxy-2,6-dimethyl-phenyl)-propionyl]-1,2,3,4-tetrahydro-isoquinoline-3-carboxylic acid phenylcarbamoylmethyl-amide::CHEMBL501451::H-Dmt-Tic-Gly-NH-Ph

SMILES Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N1Cc2ccccc2C[C@H]1C(=O)NCC(=O)Nc1ccccc1

InChI Key InChIKey=JQERUKPESNWSQA-UHFFFAOYSA-N

Data  6 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50272081   

TargetMu-type opioid receptor(Guinea pig)
University of Cagliari

Curated by ChEMBL
LigandPNGBDBM50272081(H-Dmt-Tic-Gly-NH-Ph | 2-[2-Amino-3-(4-hydroxy-2,6-...)
Affinity DataIC50: 3.02nMAssay Description:Agonist activity at mu opioid receptor in Hartley guinea pig ileum myenteric plexus longitudinal muscle assessed as inhibition of electrically-stimul...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Mouse)
University of Cagliari

Curated by ChEMBL
LigandPNGBDBM50272081(H-Dmt-Tic-Gly-NH-Ph | 2-[2-Amino-3-(4-hydroxy-2,6-...)
Affinity DataIC50: 2.57nMAssay Description:Agonist activity at delta opioid receptor in mouse vas deferens assessed as inhibition of electrically-stimulated muscle contractionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
Vrije Universiteit Brussels

Curated by ChEMBL
LigandPNGBDBM50272081(H-Dmt-Tic-Gly-NH-Ph | 2-[2-Amino-3-(4-hydroxy-2,6-...)
Affinity DataIC50: 2.60nMAssay Description:Agonist activity at mu opioid receptor by guinea pig ileum assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Mouse)
University of Cagliari

Curated by ChEMBL
LigandPNGBDBM50272081(H-Dmt-Tic-Gly-NH-Ph | 2-[2-Amino-3-(4-hydroxy-2,6-...)
Affinity DataIC50: 3nMAssay Description:Agonist activity at delta opioid receptor by mouse vas deferens assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Vrije Universiteit Brussels

Curated by ChEMBL
LigandPNGBDBM50272081(H-Dmt-Tic-Gly-NH-Ph | 2-[2-Amino-3-(4-hydroxy-2,6-...)
Affinity DataKi:  0.0420nMAssay Description:Binding affinity to delta opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
University of Cagliari

Curated by ChEMBL
LigandPNGBDBM50272081(H-Dmt-Tic-Gly-NH-Ph | 2-[2-Amino-3-(4-hydroxy-2,6-...)
Affinity DataKi:  0.0420nMAssay Description:Displacement of [3H]deltorphin2 from delta opioid receptor in Sprague-Dawley rat brain P2 synaptosomal membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
University of Cagliari

Curated by ChEMBL
LigandPNGBDBM50272081(H-Dmt-Tic-Gly-NH-Ph | 2-[2-Amino-3-(4-hydroxy-2,6-...)
Affinity DataKi:  0.0420nMAssay Description:Binding affinity at Opioid receptor delta 1 using rat brain receptor (P2 synaptosome) assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
University of Cagliari

Curated by ChEMBL
LigandPNGBDBM50272081(H-Dmt-Tic-Gly-NH-Ph | 2-[2-Amino-3-(4-hydroxy-2,6-...)
Affinity DataKi:  0.160nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in Sprague-Dawley rat brain P2 synaptosomal membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
University of Cagliari

Curated by ChEMBL
LigandPNGBDBM50272081(H-Dmt-Tic-Gly-NH-Ph | 2-[2-Amino-3-(4-hydroxy-2,6-...)
Affinity DataKi:  0.160nMAssay Description:Binding affinity for rat brain P2 synaptosome Opioid receptor mu 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Vrije Universiteit Brussels

Curated by ChEMBL
LigandPNGBDBM50272081(H-Dmt-Tic-Gly-NH-Ph | 2-[2-Amino-3-(4-hydroxy-2,6-...)
Affinity DataKi:  0.160nMAssay Description:Binding affinity to mu opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2012
Entry Details Article
PubMed