BDBM50272054 CHEMBL4129589

SMILES C(CCOc1cccc2ccccc12)CCN1CCCCCC1

InChI Key InChIKey=CDPGITMKSDQGJF-UHFFFAOYSA-N

Data  4 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50272054   

TargetHistamine H3 receptor(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50272054(CHEMBL4129589)
Affinity DataIC50: 312nMAssay Description:Antagonist activity at human H3 receptor expressed in HEK293 cells assessed as inhibition of RAMH-induced reduction of forskolin-stimulated cAMP accu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/1/2020
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50272054(CHEMBL4129589)
Affinity DataKi:  22nMAssay Description:Displacement of [3H]N-alpha-methylhistamine from full length human H3 receptor expressed in HEK293 cell membranes after 90 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/1/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50272054(CHEMBL4129589)
Affinity DataKi:  1.84E+3nMAssay Description:Displacement of [3H]-LSD from human 5-HT6 receptor expressed in HEK293 cell membranes after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/1/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50272054(CHEMBL4129589)
Affinity DataKi:  2.61E+3nMAssay Description:Displacement of [3H]-ketanserin from human 5-HT2A receptor expressed in CHO cell membranes after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/1/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50272054(CHEMBL4129589)
Affinity DataKi:  2.80E+3nMAssay Description:Displacement of [3H]-5-carboxyamidotryptamine from human 5-HT7 receptor expressed in HEK293 cell membranes after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/1/2020
Entry Details Article
PubMed