BDBM50271948 6-Methoxy-7-[3-(4-methylpiperazin-1-yl)-propoxy]-4-(1H-benzimidazol-2-ylamino)-quinoline-3-carbonitrile::CHEMBL526321

SMILES COc1cc2c(Nc3nc4ccccc4[nH]3)c(cnc2cc1OCCCN1CCN(C)CC1)C#N

InChI Key InChIKey=DHGVOMBTMBBIFA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50271948   

TargetProto-oncogene tyrosine-protein kinase Src(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50271948(6-Methoxy-7-[3-(4-methylpiperazin-1-yl)-propoxy]-4...)
Affinity DataIC50: 133nMAssay Description:Inhibition of human recombinant cSrc by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Mouse)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50271948(6-Methoxy-7-[3-(4-methylpiperazin-1-yl)-propoxy]-4...)
Affinity DataIC50: 1.81E+4nMAssay Description:Inhibition of inducible nitric oxide synthetase in LPS-stimulated mouse ANA1 macrophagesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed