BDBM50271947 6-Methoxy-7-[2-(4-methylpiperazin-1-yl)-ethoxy]-4-(benzothiazol-2-ylamino)-quinoline-3-carbonitrile::CHEMBL499623

SMILES COc1cc2c(Nc3nc4ccccc4s3)c(cnc2cc1OCCN1CCN(C)CC1)C#N

InChI Key InChIKey=JRTQUEQNWQYBSL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50271947   

TargetProto-oncogene tyrosine-protein kinase Src(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50271947(6-Methoxy-7-[2-(4-methylpiperazin-1-yl)-ethoxy]-4-...)
Affinity DataIC50: 9.23nMAssay Description:Inhibition of human recombinant cSrc by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Mouse)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50271947(6-Methoxy-7-[2-(4-methylpiperazin-1-yl)-ethoxy]-4-...)
Affinity DataIC50: 2.18E+3nMAssay Description:Inhibition of inducible nitric oxide synthetase in LPS-stimulated mouse ANA1 macrophagesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed