BDBM50271850 CHEMBL483313::N4-(4-chloro-2-fluorophenyl)-6-(2-phenylethyl)-7Hpyrrolo[2,3-d]pyrimidine-2,4-diamine::N4-(4-chloro-2-fluorophenyl)-6-phenethyl-7H-pyrrolo[2,3-d]pyrimidine-2,4-diamine

SMILES Nc1nc(Nc2ccc(Cl)cc2F)c2cc(CCc3ccccc3)[nH]c2n1

InChI Key InChIKey=KJOGVLRVAKVBOJ-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50271850   

TargetEpidermal growth factor receptor(Human)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50271850(N4-(4-chloro-2-fluorophenyl)-6-phenethyl-7H-pyrrol...)
Affinity DataIC50: 1.32E+3nMAssay Description:Inhibition of EGFR expressed in human tumor cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 1(Human)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50271850(N4-(4-chloro-2-fluorophenyl)-6-phenethyl-7H-pyrrol...)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of VEGFR1 expressed in human tumor cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50271850(N4-(4-chloro-2-fluorophenyl)-6-phenethyl-7H-pyrrol...)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of VEGFR2 expressed in human tumor cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50271850(N4-(4-chloro-2-fluorophenyl)-6-phenethyl-7H-pyrrol...)
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of PDGFRbeta expressed in human tumor cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50271850(N4-(4-chloro-2-fluorophenyl)-6-phenethyl-7H-pyrrol...)
Affinity DataIC50: 1.32E+3nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 1(Human)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50271850(N4-(4-chloro-2-fluorophenyl)-6-phenethyl-7H-pyrrol...)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of VEGFR1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50271850(N4-(4-chloro-2-fluorophenyl)-6-phenethyl-7H-pyrrol...)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50271850(N4-(4-chloro-2-fluorophenyl)-6-phenethyl-7H-pyrrol...)
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of PDGFRbetaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed