BDBM50271765 3-(4-{3-[4-(3-Carboxy-acryloylamino)-phenoxy]-phenoxy}-phenylcarbamoyl)-acrylic acid::4,4'-(4,4'-(1,3-phenylenebis(oxy))bis(4,1-phenylene))bis(azanediyl)bis(4-oxobut-2-enoic acid)::CHEMBL482498

SMILES OC(=O)\C=C\C(=O)Nc1ccc(Oc2cccc(Oc3ccc(NC(=O)\C=C\C(O)=O)cc3)c2)cc1

InChI Key InChIKey=HZFPOTBCYPWQSH-UHFFFAOYSA-N

Data  3 KI  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50271765   

TargetLysophosphatidic acid receptor 1(Human)
The University of Memphis

Curated by ChEMBL
LigandPNGBDBM50271765(4,4'-(4,4'-(1,3-phenylenebis(oxy))bis(4,1-phenylen...)
Affinity DataIC50: 2.74E+4nMAssay Description:Antagonist activity at LPA1 receptor expressed in rat RH7777 cells assessed as inhibition of LPA-induced intracellular calcium concentrationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetLysophosphatidic acid receptor 2(Human)
The University of Memphis

Curated by ChEMBL
LigandPNGBDBM50271765(4,4'-(4,4'-(1,3-phenylenebis(oxy))bis(4,1-phenylen...)
Affinity DataIC50: 8.90nMAssay Description:Antagonist activity at LPA2 receptor expressed in rat RH7777 cells assessed as inhibition of LPA-induced intracellular calcium concentrationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetLysophosphatidic acid receptor 3(Human)
The University of Memphis

Curated by ChEMBL
LigandPNGBDBM50271765(4,4'-(4,4'-(1,3-phenylenebis(oxy))bis(4,1-phenylen...)
Affinity DataIC50: 1.23E+3nMAssay Description:Antagonist activity at LPA3 receptor expressed in rat RH7777 cells assessed as inhibition of LPA-induced intracellular calcium concentrationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetLysophosphatidic acid receptor 2(Human)
The University of Memphis

Curated by ChEMBL
LigandPNGBDBM50271765(4,4'-(4,4'-(1,3-phenylenebis(oxy))bis(4,1-phenylen...)
Affinity DataIC50: 9nMAssay Description:Antagonist activity at LPA2 receptor expressed in rat RH7777 cells assessed as inhibition of LPA-induced intracellular calcium responseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetLysophosphatidic acid receptor 3(Human)
The University of Memphis

Curated by ChEMBL
LigandPNGBDBM50271765(4,4'-(4,4'-(1,3-phenylenebis(oxy))bis(4,1-phenylen...)
Affinity DataIC50: 1.23E+3nMAssay Description:Antagonist activity at LPA3 receptor expressed in rat RH7777 cells assessed as inhibition of LPA-induced intracellular calcium responseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetLysophosphatidic acid receptor 1(Human)
The University of Memphis

Curated by ChEMBL
LigandPNGBDBM50271765(4,4'-(4,4'-(1,3-phenylenebis(oxy))bis(4,1-phenylen...)
Affinity DataIC50: 2.74E+4nMAssay Description:Antagonist activity at LPA1 receptor expressed in rat RH7777 cells assessed as inhibition of LPA-induced intracellular calcium responseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetLysophosphatidic acid receptor 2(Human)
The University of Memphis

Curated by ChEMBL
LigandPNGBDBM50271765(4,4'-(4,4'-(1,3-phenylenebis(oxy))bis(4,1-phenylen...)
Affinity DataKi:  7.20nMAssay Description:Antagonist activity at LPA2 receptor expressed in rat RH7777 cells assessed as inhibition of LPA-induced intracellular calcium concentrationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetLysophosphatidic acid receptor 3(Human)
The University of Memphis

Curated by ChEMBL
LigandPNGBDBM50271765(4,4'-(4,4'-(1,3-phenylenebis(oxy))bis(4,1-phenylen...)
Affinity DataKi:  310nMAssay Description:Antagonist activity at LPA3 receptor expressed in rat RH7777 cells assessed as inhibition of LPA-induced intracellular calcium concentrationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetLysophosphatidic acid receptor 1(Human)
The University of Memphis

Curated by ChEMBL
LigandPNGBDBM50271765(4,4'-(4,4'-(1,3-phenylenebis(oxy))bis(4,1-phenylen...)
Affinity DataKi:  1.35E+4nMAssay Description:Antagonist activity at LPA1 receptor expressed in rat RH7777 cells assessed as inhibition of LPA-induced intracellular calcium concentrationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed