BDBM50271760 CHEMBL482489::N4-(3-Bromophenyl)-6-[2-(2-chlorophenyl)ethyl]-7H-pyrrolo[2,3-d]pyrimidine-2,4-diamine

SMILES Nc1nc(Nc2cccc(Br)c2)c2cc(CCc3ccccc3Cl)[nH]c2n1

InChI Key InChIKey=ZFOINLDOMHQFOQ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50271760   

TargetEpidermal growth factor receptor(Human)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50271760(N4-(3-Bromophenyl)-6-[2-(2-chlorophenyl)ethyl]-7H-...)
Affinity DataIC50: 3.40E+3nMAssay Description:Inhibition of EGFR expressed in human tumor cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 1(Human)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50271760(N4-(3-Bromophenyl)-6-[2-(2-chlorophenyl)ethyl]-7H-...)
Affinity DataIC50: 3.27E+4nMAssay Description:Inhibition of VEGFR1 expressed in human tumor cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50271760(N4-(3-Bromophenyl)-6-[2-(2-chlorophenyl)ethyl]-7H-...)
Affinity DataIC50: 4.23E+4nMAssay Description:Inhibition of VEGFR2 expressed in human tumor cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50271760(N4-(3-Bromophenyl)-6-[2-(2-chlorophenyl)ethyl]-7H-...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of PDGFRbeta expressed in human tumor cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed