BDBM50271594 2-(2-methyl-1H-imidazol-1-yl)-1-(4-nitrophenyl)ethanone::CHEMBL447987

SMILES Cc1nccn1CC(=O)c1ccc(cc1)[N+]([O-])=O

InChI Key InChIKey=SDQNOFICLCGYFJ-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50271594   

TargetNitric oxide synthase, brain(Human)
Instituto De QuíMica MéDica

Curated by ChEMBL
LigandPNGBDBM50271594(2-(2-methyl-1H-imidazol-1-yl)-1-(4-nitrophenyl)eth...)
Affinity DataKi:  7.40E+4nMAssay Description:Inhibition of nNOS assessed as conversion of L-[3H]arginine to L-[3H]citrullineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Rat)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50271594(2-(2-methyl-1H-imidazol-1-yl)-1-(4-nitrophenyl)eth...)
Affinity DataKi:  7.40E+4nMAssay Description:Inhibition of rat recombinant nNOS expressed in baculovirus-infected Sf9 cells assessed as conversion of oxyhemoglobin to methemoglobin by UV spectro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Mouse)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50271594(2-(2-methyl-1H-imidazol-1-yl)-1-(4-nitrophenyl)eth...)
Affinity DataKi: >2.00E+6nMAssay Description:Inhibition of C57BL/6 mouse eNOS assessed as conversion of oxyhemoglobin to methemoglobin by UV spectrophotometer analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed