BDBM50271441 CHEMBL505502::Tyr-Pro-Phe-Phe-OCH2CH3

SMILES CCOC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H]1CCCN1C(=O)[C@@H](N)Cc1ccc(O)cc1

InChI Key InChIKey=JKMFJIMTIXQDHF-UHFFFAOYSA-N

Data  4 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50271441   

TargetDelta-type opioid receptor(Mouse)
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50271441(Tyr-Pro-Phe-Phe-OCH2CH3 | CHEMBL505502)
Affinity DataIC50: 63.8nMAssay Description:Agonist activity at delta opioid receptor in mouse vas deferens assessed as inhibition of electrically-stimulated contractionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50271441(Tyr-Pro-Phe-Phe-OCH2CH3 | CHEMBL505502)
Affinity DataIC50: 64.4nMAssay Description:Agonist activity at mu opioid receptor in guinea pig ileum assessed as inhibition of electrically-stimulated contractionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50271441(Tyr-Pro-Phe-Phe-OCH2CH3 | CHEMBL505502)
Affinity DataKi:  15.0nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in rat brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50271441(Tyr-Pro-Phe-Phe-OCH2CH3 | CHEMBL505502)
Affinity DataKi:  15nMAssay Description:Binding affinity to MOP (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetDelta-type opioid receptor(Rat)
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50271441(Tyr-Pro-Phe-Phe-OCH2CH3 | CHEMBL505502)
Affinity DataKi:  2.94E+3nMAssay Description:Displacement of [3H]DPDPE from delta opioid receptor in rat brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50271441(Tyr-Pro-Phe-Phe-OCH2CH3 | CHEMBL505502)
Affinity DataKi:  2.94E+3nMAssay Description:Binding affinity to DOP (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed