BDBM50271362 CHEMBL4126395::US12012467, Compound DI-417

SMILES CCC(=O)N[C@@H](Cc1nc2ccc(Cl)cc2s1)C(=O)N[C@@H](C1CCNCC1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]1CCOc2ccccc12

InChI Key InChIKey=MCQNVYUWEOZFGZ-UHFFFAOYSA-N

Data  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50271362   

TargetDCN1-like protein 1(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50271362(CHEMBL4126395 | US12012467, Compound DI-417)
Affinity DataKd:  1.47E+3nMAssay Description:Binding affinity to biotin labeled recombinant N-terminal His6-tagged human DCN1 (58 to 259 residues) expressed in Escherichia coli Rosetta2 cells by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2020
Entry Details Article
PubMed
TargetDCN1-like protein 1(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50271362(CHEMBL4126395 | US12012467, Compound DI-417)
Affinity DataIC50: 5.00E+3nMAssay Description:The Fluorescence Polarization (FP) competitive binding assays were performed to accurately determine the binding affinities of our DCN1 inhibitors. A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2024
Entry Details
Go to US Patent