BDBM50271314 2-(3-(6-hydroxynaphthalen-2-yl)propanamido)cyclohex-1-enecarboxylic acid::CHEMBL482698

SMILES OC(=O)C1=C(CCCC1)NC(=O)CCc1ccc2cc(O)ccc2c1

InChI Key InChIKey=ALVRTKGVHQDHNJ-UHFFFAOYSA-N

Data  1 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50271314   

TargetHydroxycarboxylic acid receptor 2(Human)
Latvian Institute of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50271314(2-(3-(6-hydroxynaphthalen-2-yl)propanamido)cyclohe...)
Affinity DataEC50:  1.90E+3nMAssay Description:Agonist activity at human HCA2 receptor expressed in Flp-In-293 cells assessed as inhibition of forskolin-induced cAMP accumulation after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2015
Entry Details Article
PubMed
TargetHydroxycarboxylic acid receptor 2(Human)
Latvian Institute of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50271314(2-(3-(6-hydroxynaphthalen-2-yl)propanamido)cyclohe...)
Affinity DataIC50: 8nMAssay Description:Displacement of [3H]niacin from human niacin receptor expressed in CHO-KI cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetHydroxycarboxylic acid receptor 2(Human)
Latvian Institute of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50271314(2-(3-(6-hydroxynaphthalen-2-yl)propanamido)cyclohe...)
Affinity DataEC50:  76nMAssay Description:Agonist activity at human niacin receptor expressed in CHO-KI cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed