BDBM50271204 CHEMBL3400288

SMILES FC(F)c1nc2ccccc2n1-c1nc(nc(n1)N1CCOCC1)N1CCNCC1

InChI Key InChIKey=OGBPVMMFHBOWQT-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50271204   

LigandPNGBDBM50271204(CHEMBL3400288)
Affinity DataIC50: 1.09E+3nMAssay Description:Inhibition of PI3Kbeta (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2020
Entry Details Article
PubMed
LigandPNGBDBM50271204(CHEMBL3400288)
Affinity DataIC50: 180nMAssay Description:Inhibition of recombinant human full length His-tagged PI3K p110alpha/p85alpha expressed in baculovirus expression system coexpressing PIK3R1 by TR-F...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2020
Entry Details Article
PubMed
LigandPNGBDBM50271204(CHEMBL3400288)
Affinity DataIC50: 142nMAssay Description:Inhibition of recombinant human full length His-tagged PI3K p110delta/p85alpha expressed in baculovirus expression system coexpressing PIK3R1 by TR-F...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2020
Entry Details Article
PubMed
LigandPNGBDBM50271204(CHEMBL3400288)
Affinity DataIC50: 1.87E+3nMAssay Description:Inhibition of recombinant human full length His-tagged PI3K p110gamma expressed in baculovirus expression system by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2020
Entry Details Article
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
The University of Michigan Medical School

Curated by ChEMBL
LigandPNGBDBM50271204(CHEMBL3400288)
Affinity DataIC50: 180nMAssay Description:Inhibition of human PI3Kalpha by TR-FRET based Adapta assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
LigandPNGBDBM50271204(CHEMBL3400288)
Affinity DataIC50: 1.09E+3nMAssay Description:Inhibition of human PI3Kbeta by TR-FRET based Adapta assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
LigandPNGBDBM50271204(CHEMBL3400288)
Affinity DataIC50: 1.87E+3nMAssay Description:Inhibition of human PI3Kgamma by TR-FRET based Adapta assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
The University of Michigan Medical School

Curated by ChEMBL
LigandPNGBDBM50271204(CHEMBL3400288)
Affinity DataIC50: 142nMAssay Description:Inhibition of human PI3Kdelta by TR-FRET based Adapta assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed