BDBM50271162 CHEMBL4127683

SMILES Oc1c(F)c(Cl)cc2c1N=C(Nc1cccc3[nH]ncc13)NS2(=O)=O

InChI Key InChIKey=UAHVXIUTSRUJDU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50271162   

Target5'-nucleotidase(Human)
Therachem Research Medilab (India)

Curated by ChEMBL
LigandPNGBDBM50271162(CHEMBL4127683)
Affinity DataIC50: 16nMAssay Description:Inhibition of human flag-tagged CD73 Thr376Ala mutant (1 to 552 residues) assessed as reduction in conversion of AMP to adenosine incubated for 10 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2020
Entry Details Article
PubMed
Target5'-nucleotidase(Human)
Therachem Research Medilab (India)

Curated by ChEMBL
LigandPNGBDBM50271162(CHEMBL4127683)
Affinity DataIC50: 15nMAssay Description:Inhibition of human recombinant CD73More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed