BDBM50271124 CHEMBL4126836::US10399961, Example 13

SMILES C[C@H]1CCN(C1)c1ccc(Cn2cc(cn2)C(=O)N[C@@H]2CCc3nc(N)ccc23)cn1

InChI Key InChIKey=VBXFERGVTGHWOF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50271124   

TargetPlasma kallikrein(Human)
Therachem Research Medilab (India)

Curated by ChEMBL
LigandPNGBDBM50271124(CHEMBL4126836 | US10399961, Example 13)
Affinity DataIC50: 19nMAssay Description:Inhibition of human plasma kallikrein using H-Pro-Phe-Arg-AMC as substrate after 1 hr by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2020
Entry Details Article
PubMed
TargetPlasma kallikrein(Human)
Therachem Research Medilab (India)

Curated by ChEMBL
LigandPNGBDBM50271124(CHEMBL4126836 | US10399961, Example 13)
Affinity DataIC50: 19nMAssay Description:Human KLKB1 (0.01 U/mL; Enzyme Research Laboratories) or rat KLKB1 (0.625 nM; produced in-house) was incubated for 1 hr at Room Temperature with 0.10...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/27/2020
Entry Details
Go to US Patent