BDBM50271046 CHEMBL4127005

SMILES O=C1C=C(CSC(=S)N2CCN(CC2)c2ccccc2)C(=O)c2ccccc12

InChI Key InChIKey=XYRBEHRCJZHVHL-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50271046   

TargetPyruvate kinase PKLR(Human)
Peking University Health Science Center

Curated by ChEMBL
LigandPNGBDBM50271046(CHEMBL4127005)
Affinity DataIC50: 3.80E+3nMAssay Description:Inhibition of recombinant human N-terminal His-tagged PKL expressed in Escherichia coli preincubated for 15 mins followed by PEP/NADH addition measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2020
Entry Details Article
PubMed
TargetPyruvate kinase PKM(Human)
Peking University Health Science Center

Curated by ChEMBL
LigandPNGBDBM50271046(CHEMBL4127005)
Affinity DataIC50: 6.26E+3nMAssay Description:Inhibition of recombinant human N-terminal His-tagged PKM1 expressed in Escherichia coli BL21 preincubated for 15 mins followed by PEP/NADH addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2020
Entry Details Article
PubMed
TargetPyruvate kinase PKM(Human)
Peking University Health Science Center

Curated by ChEMBL
LigandPNGBDBM50271046(CHEMBL4127005)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of recombinant human N-terminal His-tagged PKM2 expressed in Escherichia coli BL21 preincubated for 15 mins followed by PEP/NADH addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2020
Entry Details Article
PubMed